Miltenyi Biotec

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The CliniMACS Prodigy Platform supports a wide variety of cell processing applications.

Learn more about the highlighted processes below or get an overview of the full potential of the platform and all available cell and gene therapy workflows.

The CliniMACS Prodigy is an automated cell processing instrument designed for the efficient production of GMP-compliant cell and gene therapies. It addresses the manufacturing challenges of autologous and allogeneic therapies by simplifying workflows through automation and integration. With more than 300 custom workflows and use in more than 150 clinical trials, it has become the no. 1 platform for clinical and commercial cell manufacturing.

The CliniMACS Prodigy streamlines complex processes from cell washing, separation, genetic modification, and expansion to the formulated final cell product. Its versatility allows for standard or custom applications, making it ideal for a wide range of therapies, including T cell, NK cell, and stem cell treatments. Learn more about its full potential from clinical to commercial use.

Smart solutions for automated manufacturing

  • Preinstalled and verified applications for a wide range of cell processes
  • Customizable processes for tailor-made automated workflows
  • Intuitive software for easy on-screen navigation and operation
  • Compliance with 21 CFR Part 11 & Annex 11
  • Local network connectivity for automated file transfer, e-mail notifications, and more
  • Multi-instrument alignment at multiple sites for advanced scalability
Dimensions 73.5 cm × 40 cm × 48 cm (w × d × h)
Weight approx. 70 kg
Input voltage 100–240 V~
Power consumption 810 W
Frequency 50/60 Hz
Pump speed 2–400 mL/min
Atmosphere control Gas mix unit for CO2, compressed air, and N2; min. pressure: 1 bar, max. pressure: 2.5 bar
Temperature control +4 °C to +38 °C
Centrifugation Max. 2,500 rpm (400×g)
Microscope camera Max. magnification: 400-fold
Monitor 10.1” TFT touchscreen
MACS tube sealer For sealing CliniMACS Prodigy Tubing Sets PVC tubes
Types of starting material Leukapheresis, bone marrow, cryopreserved PSCs
Available cell processing steps Cell washing, density gradient centrifugation, cell activation, fluorescent antibody labeling of cells, cell depletion and / or enrichment via magnetic cell separation, viral transduction, cell expansion, expansion and differentiation of adherent cells, cell culture and medium exchange, formulation of final cell product
Tubing Sets and accessories Dedicated CliniMACS Prodigy Tubing Sets and Accessories available
IPC/QC Integrated IPC/QC sampling pouches allow sterile sample removal
Manufacture and availability Manufactured in Germany and shipped worldwide